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目的探讨血清镁离子(magnesium ions,Mg)与C-反应蛋白(c-reactive protein,CRP)在妊娠期糖尿病(ges-tational Diabetes Mellitus,GDM)中的相关性。方法 GDM组48例,NGT(normal glucose tolerance)组48例,测定两组研究对象空腹血糖(fasting blood glucose,FBG)、血清Mg2+及CRP水平,统计数据进行相关性分析。结果 GDM组中血清Mg2+水平与CRP浓度及FBG水平呈显著负相关(均P﹤0.01),CRP浓度与FBG水平呈显著正相关(P﹤0.01)。结论低血镁和高CRP与妊娠期糖尿病的FBG水平密切相关,同时检测血清Mg2+和CRP有利于妊娠期糖尿病的早期发现,并指导治疗。
Objective To investigate the correlation between serum magnesium (Mg) and c-reactive protein (CRP) in ges-tational diabetes mellitus (GDM). Methods 48 cases of GDM group and 48 cases of NGT (normal glucose tolerance) group were divided into two groups. The fasting blood glucose (FBG), serum Mg2 + and CRP level were measured in two groups. The correlation analysis was made between the two groups. Results There was a significant negative correlation between serum Mg2 + level and CRP level and FBG level in GDM group (all P <0.01). CRP level was positively correlated with FBG level (P <0.01). Conclusion Low serum magnesium and high CRP levels are closely related to FBG levels in gestational diabetes mellitus. Simultaneous detection of serum Mg2 + and CRP is beneficial for the early detection of gestational diabetes mellitus and guiding the treatment.