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以往研究发现强直性肌营养不良症(MyD)患者丘脑内包涵体(TIs)的发生率明显高于对照组,提示丘脑内包涵体可能与强直性肌营养不良症的病因有关。为此,作者对8个MyD患者和9个非MyD患者丘脑内包涵体的免疫组化特性进行研究,以明确其神经病理特征。 结果MyD患者丘脑内包涵体的发生率为12.8±4.2％,明显高于对照组(P<0.001)。光镜下可见丘脑
Previous studies found that the incidence of thalamic inclusions (TIs) in patients with Myotonic Dystrophy (MyD) was significantly higher than that of the control group, suggesting that thalamic inclusion bodies may be related to the etiology of myotonic dystrophy. To do this, we studied the immunohistochemical properties of thalamic inclusion bodies in eight MyD patients and nine non-MyD patients to identify their neuropathological features. Results The incidence of thalamic inclusion in MyD patients was 12.8 ± 4.2%, which was significantly higher than that of the control group (P <0.001). Light microscopic view of the thalamus