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目的探讨双源CT双能量扫描肺灌注成像(DEPI)和最小密度投影(MinP)的临床诊断价值。方法对临床疑肺动脉栓塞患者行双源CT双能量扫描,将扫描后数据传至工作站进行灌注成像分析;对肺组织灌注定量分析,进行统计学处理,同一患者的双侧比较行配对t检验,不同组别之间的比较行独立样本t检验;以融合数据的CTPA图像为标准,分别计算DEPI、MinP图像诊断肺栓塞的敏感度,特异度,阴性预测值,阳性预测值,比较采用配对卡方检验。结果灌注定量分析显示对照组双肺及双肺上、中、下部分别比较均无统计学意义(P>0.05);肺栓塞组灌注定量分析显示全肺及中、下肺比较均有统计学意义(P<0.05);DEPI和MinP图像与CTPA在诊断肺栓塞方面有较高的一致性。结论双源CT双能量扫描可用于肺栓塞的诊断,尤其有利于其早期发现和精确解剖定位。
Objective To investigate the clinical value of double-source CT dual-energy scanning lung perfusion imaging (DEPI) and minimal density projection (MinP). Methods Dual-source CT dual-energy scanning was performed in patients with suspected pulmonary artery embolism. The scanned data were transmitted to a workstation for perfusion imaging analysis. Quantitative analysis of lung perfusion was performed and statistical analysis was performed. Two-sided paired t- The comparison of different groups was performed by independent sample t-test. The sensitivity, specificity, negative predictive value and positive predictive value of DEPI and MinP images were calculated respectively based on the fusion data of CTPA images. Party test. Results The perfusion quantitative analysis showed that there was no significant difference in the upper, middle and lower lungs between the control group and the middle and lower lungs (P> 0.05). The quantitative analysis of perfusion in the pulmonary embolism group showed that the whole lung, middle and lower lungs were statistically significant (P <0.05). The DEPI and MinP images were in good agreement with CTPA in the diagnosis of pulmonary embolism. Conclusion Dual-source CT dual-energy scan can be used for the diagnosis of pulmonary embolism, especially for its early detection and accurate anatomical positioning.