结核病接触者调查

• 作 者: MARY R.REICHLER SUE ETKIND ZACHARY TAYLOR KENNETH G.CASTRO 于兰
• 机 构: Division of Tuberculosis Elimination Centers for Disease Control and Prevention Atlanta, GA, USA,Mas
• 出 处: 结核与肺部疾病杂志(中文版)
• 发表日期: 2004年01期
• 关键词: 结核病控制 接触者 活动性结核病 隐性感染者 高危人群 结核感染 涂阳病人 发现率 结核菌素皮试 悬浮微粒

结核病是导致成人死亡的主要传染病之一。每年全球有1000万人发生结核病,近200万人死于结核病1 、2。引起结核病的结核杆菌是由传染性结核病人的飞沫悬浮微粒传播给暴露的接触者的。这样的暴露接触之后,1-2％的接触者迅速发生活动性结核病,1/3的接触者成为隐性感染者,2/3的接触者并不会发生感染3、4。5-10％的隐性感染者将在其一生当中的任何时候发病。因此,传染性结核病人的近期接触者是结核病的高危人群3、4。

Tuberculosis is one of the major infectious diseases that kill adults. Every year, 10 million people worldwide have tuberculosis and nearly 2 million people have died of tuberculosis1,2. Mycobacterium tuberculosis, which causes tuberculosis, is transmitted to exposed contacts by droplets of infectious TB patients. After exposure to such exposure, active tuberculosis occurs rapidly in 1-2% of the contacts, and one in three contacts becomes a latent infection, and two thirds of the contacts are not infected. 3.4.5-10% The tactile infection will develop at any time of its life. As a result, the recent contacts of infectious TB patients are at high risk for tuberculosis 3,4.