【摘 要】
：
Trichomonas vaginalis,a zoonotic anaerobic parasite first discovered in the secretions of vaginitis patients in 1836,is mainly transmit-ted through sexual activities.In addition,T.vaginalis can also be transmitted through indirect contact in public swimmi
【机 构】
：
Key Laboratory of Zoonosis Research,Ministry of Education,College of Veterinary Medicine,Jilin Unive
论文部分内容阅读
Trichomonas vaginalis,a zoonotic anaerobic parasite first discovered in the secretions of vaginitis patients in 1836,is mainly transmit-ted through sexual activities.In addition,T.vaginalis can also be transmitted through indirect contact in public swimming pools,toi-lets,bathtubs,etc.Infected females suffer from diseases such as vaginitis,urethritis,miscarriage,and premature birth,while infected males are mostly asymptomatic carriers or with chronic urethral inflammation and prostate inflammation,which can cause infertil-ity in severe cases.Infection with T.vaginalis increases the risk of human immunodeficiency virus infection [1].Polymorphonuclear neutrophils (PMNs) are the most abundant in white blood cells,accounting for more than 60％,and play important roles in the nat-ural immune system and form the first defense line of hosts against microbial pathogens [2].There are two ways in which PMNs kill pathogens:one is the way to directly phagocytose pathogens and the other is to release the nuclear DNA into the extracellular DNA through the rearrangement of the cytoskeleton,and capture the pathogens,which is called neutrophil extracellular traps (NETs)and this method of death is called NETosis [3].Previous studies have focused on the effects of NETs on bacteria,fungi,and viruses,while recent studies focused on the effects of NETs on parasites such as Toxoplasma gondii,Neospora caninum,and Leishmania [4-6].
其他文献
Resveratrol (RSV) could promote osteogenic activity,but its clinical application has been hampered in view of its poor bioavailability.Therefore,it is desirable to identify with certainty the molecular target of its bone mass boosting function,which is cr
Osteocytes are the main sensitive cells in bone remodeling due to their potent functional cell pro-cesses from the mineralized bone matrix to the bone surface and the bone marrow.Neighboring osteocytes communicate with each other by these cell processes t
The widespread use of chlorothalonil (CTL) has caused environmental residues and food contami-nation.Although the intestinal epithelial barrier (IEB) is directly involved in the metabolism and transportation of various exogenous compounds,there are few st
We have previously reported that the long-term exposure of Isocarbophos,a kind of organophos-phorus compounds,induces vascular dementia (VD) in rats.Studies have also shown that organophosphorus compounds have adverse effects on offsprings.Vitamin B6 is a
Lipid metabolism disorder caused by the upregulation of lipogenic genes is a typical feature of prostate cancer.The synthesis of fatty acids is enhanced to accelerate the development of prostate cancer and is considered as a potential therapeutic target.E
Multiple myeloma (MM) is an incurable disease characterized by malignant plasma cell clonal expansion in the bone marrow;therefore,inhibiting the proliferation of plasma cells is an impor-tant approach to overcome the progression of MM.Quercetin (Que) is
The dynamic and reversible regulation roles of m6A modification and the characterization of m6A readers have provided new insights into spermatogenesis at the post-transcriptional level.YTHDF2,as an meA reader,has been reported to mediate the meA-containi
Vascularization is an important early indicator of osteogenesis involving biomaterials.Bone repair and new bone formation are associated with extensive neovascularization.Silicon-based bioma-terials have attracted widespread attention due to their rapid v
The 5-year survival rate of lung cancer is one of the lowest among various malignant tumors.Long noncoding RNAs (lncRNAs),noncoding RNAs longer than 200 nucleotides,can function either as tumor suppressors or as oncogenes.The aim of this study is to inves
BACE1 antisense RNA (BACE1-AS) is implicated in promoting cell proliferation in different types of tumors.However,the function and mechanism of BACE1-AS in hepatocellular carcinoma (HCC)are still unclear.In the present study,we found that the relative exp