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背景过去40年,食物过敏及食用海产品(鱼、软体动物和贝壳类)呈增长趋势。目前海产品过敏为美国和澳大利亚两国过敏反应症的主要原因。然而,有关临床表现及海产品过敏管理发表的研究数据有限。目的对大数目儿童海产品过敏的特征做出描述。方法人群回顾性研究,我们收集了2006—2009年因海产品反应来第三变态反应服务部就诊所有儿童的数据。结果有167例儿童定义为海产品临床反应和(或)阳性食品激发免疫反应(男性103例,占62%)。94%有并存特应性疾病证据。涉及海产品最多是对虾/小虾。1/5对海产品有过敏史。对贝壳类过敏的儿童,>50%对非贝壳鱼类耐受。对鱼过敏的儿童对其他鱼类的致敏性极常见。至少有1/3报告对两种鱼有临床反应;16%对鱼蒸汽出现过敏症状。对鲔鱼和鲑鱼过敏的儿童,至少有21%对鱼罐头耐受。结论海产食品是澳大利亚儿童食品过敏比较常见和重要的原因,过敏症呈高发率。
Background Over the past 40 years, food allergies and the consumption of seafood (fish, molluscs and shellfish) have been on the rise. At present, seafood allergy is the main cause of allergic reactions in the United States and Australia. However, there are limited published data on clinical manifestations and seafood allergy management. Aim To characterize the allergies of large numbers of children’s seafood. Method Population Retrospective study, we collected data on all children in the Third Allergy Services Department who responded to the seafood reaction in 2006-2009. Results A total of 167 children were defined as clinical responses to seafood and / or positive food-induced immune responses (103 males, 62%). 94% had evidence of atopic disease. Most seafood products involved are shrimp / shrimp. 1/5 allergic to seafood. Children allergic to shellfish,> 50% of non-shellfish tolerance. Children allergic to fish sensitization of other fish is extremely common. At least one-third of the reports reported clinical responses to both species of fish; 16% reported allergies to fish steam. At least 21% of children allergic to anchovy and salmon are resistant to canned fish. Conclusion Seafood is a common and important cause of food allergy in children in Australia. Allergies are highly frequent.