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作者报告一例混合性结缔组织病(MCTD)患者,其血清内可溶性免疫复合物升高,且升高与疾病的活动和病程密切相关.中等剂量的倍他米松能降低免疫复合物的水平,并使临床症状改善.患者,女性,33岁,1971年7月出现雷诺氏现象及手、足、膝部进行性关节炎,约2年后发现双眼及口腔干燥,面部蝶形红斑.血沉142mm/小时,LE细胞(-),尿正常.类风湿因子和C反应蛋白(+),白细胞7000,分类正常范围,高球蛋白血症(48.2%).
The authors report that elevated serum soluble immune complexes in a patient with mixed connective tissue disease (MCTD) are associated with increased disease activity and duration, and that moderate doses of betamethasone can reduce immune complex levels and The clinical symptoms improved in patients, women, 33 years old, July 1971 Raynaud’s phenomenon and arthritis in hands, feet and knees, about 2 years after the discovery of both eyes and dry mouth, facial butterfly erythema. ESR 142mm / Hours, LE cells (-), normal urine, rheumatoid factor and C-reactive protein (+), white blood cells 7000, normal range of classification, hypergammaglobulinemia (48.2%).