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梭曼、沙林是G类毒剂的典型代表,对胆碱酯酶都有很强的抑制作用,但两者又不完全相同。我们测定了鸭血清丁酰胆碱酯酶的Km值,并测定了梭曼、沙林对该酶抑制反应的解离常数Kd、膦酰化常数K_2
Soman, sarin is a typical representative of G class of agents, have a strong inhibitory effect on cholinesterase, but the two are not exactly the same. We measured the Km value of duck serum butyrylcholinesterase and determined the dissociation constant Kd of soman and sarin to the enzyme inhibition reaction and the phosphonylation constant K_2