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在吡啶羧酸铬 (Ⅲ )中，以吡啶－ 2－甲酸 (即皮可啉酸， picolinic acid)铬的添加饲养功效最好。合成吡啶－ 2－甲酸铬的关键步骤是配体吡啶－ 2－甲酸的合成，通常用氧化剂 (如高锰酸钾 )氧化 2－甲基吡啶制得吡啶－ 2－甲酸的盐酸盐，且产率不高 (≤ 50％ )。我们改进了吡啶
In the chromium (III) picolinate, pyridine-2-formic acid (ie, picolinic acid) was best added with chromium. The key step in the synthesis of pyridine-2-carboxylic acid chromium is the synthesis of the ligand pyridine-2-carboxylic acid. Pyridine-2-carboxylic acid hydrochloride is usually prepared by oxidizing 2-picoline with an oxidizing agent such as potassium permanganate and Yield is not high (≤ 50%). We have improved the pyridine