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肿瘤发病率逐年升高,且呈年轻化趋势,已成为危害人类健康的主要疾病之一。关于肿瘤的发病机制目前尚未完全明确,但有研究证实与血循环中高浓度的内脏脂肪素(Visfatin)有关。vis-fatin是新近发现的一种主要由内脏脂肪细胞分泌的可在体内多种组织器官中呈广泛表达的脂肪细胞因子,通过其活跃的生物学活性参与肿瘤等多种疾病的发生、发展,其发挥作用的机制为攻克肿瘤提供了新的方向与靶点。
The incidence of cancer increased year by year, and the younger trend, has become one of the major diseases endangering human health. The pathogenesis of the tumor is not yet completely clear, but studies have shown that the high circulating concentrations of visfatin (Visfatin). Vis-fatin is a newly discovered adipocytokine secreted by visceral adipose cells that can be widely expressed in many tissues and organs of the body. Through its active biological activity, vis-fatin participates in the occurrence and development of many diseases such as tumors, Its mechanism of action provides a new direction and target to overcome the tumor.