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目的:观察大承气汤保留灌肠治疗脓毒症合并肠麻痹患者中的临床疗效。方法:60例脓毒症合并肠麻痹患者随机分为治疗组和对照组,对照组(n=30)在集束化治疗脓毒症的基础上,予胃肠减压、维持水电解质、酸碱平衡及抑酸保护胃肠道黏膜等对症治疗;治疗组(n=30)在对照组治疗基础上加用大承气汤保留灌肠。结果:治疗组临床有效率为96.67%,对照组临床有效率为76.67%,差异有统计学意义(P<0.05)。治疗组患者肠鸣音出现时间及首次肛门排气时间、排便时间均明显早于对照组,差异均具有显著统计学意义(P<0.01)。结论:大承气汤保留灌肠能有效改善脓毒症合并肠麻痹患者的临床症状,缩短患者胃肠功能恢复时间,是治疗脓毒症合并肠麻痹的有效方法。
Objective: To observe the clinical efficacy of Dachengqi decoction for preserving enema in patients with sepsis complicated with intestinal paralysis. Methods: Sixty patients with sepsis complicated with intestinal paralysis were randomly divided into treatment group and control group. The control group (n = 30) was treated on the basis of intensive treatment of sepsis. The patients were given gastrointestinal decompression, water and electrolyte maintenance, Balance and acid suppression to protect the gastrointestinal mucosa and other symptomatic treatment; treatment group (n = 30) in the control group based on the treatment with Dachengqi Decoction retention enema. Results: The clinical effective rate was 96.67% in the treatment group and 76.67% in the control group, the difference was statistically significant (P <0.05). The onset time of bowel sounds and the time of first anal exhaust and defecation in the treatment group were significantly earlier than those in the control group, with significant differences (P <0.01). Conclusion: Dachengqi decoction retention enema can effectively improve the clinical symptoms of patients with sepsis complicated with intestinal paralysis and shorten the recovery time of patients with gastrointestinal function, is an effective method for the treatment of sepsis with intestinal paralysis.