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视网膜母细胞瘤为儿童最常见的眼内恶性瘤,偶而瘤体可产生坏死、钙化和退化。Verhoeff于1966年即提出肿瘤退化的典型模式,从而肿瘤细胞过度增殖、缺血、营养供应不足则成为肿瘤退化的机制。虽钙化为该肿瘤的一般特征,且常是X线诊断的一项标志,然钙沉着的精确部位和细胞学机转尚未确定,进而瘤细胞中钙沉着直至坏死的关系也不清楚。本文系对有钙化的视网膜母细胞瘤的3眼作光镜、电镜俭查,并进行了电探测显微分析。材料和方法被摘除了3眼立即剖开置于McGoroeut Trump氏固定液中。钙检查用Von Kosssa氏
Retinoblastoma is the most common intraocular malignant tumor in children, and occasionally the tumor can produce necrosis, calcification and degeneration. Verhoeff in 1966 proposed a typical model of tumor degeneration, and thus excessive proliferation of tumor cells, ischemia, lack of nutrients has become a mechanism of tumor degradation. Although calcification is a general feature of the tumor and is often a hallmark of X-ray diagnosis, the precise location of calcifications and cytological mechanisms have not yet been established, and the relationship between calcifications in neoplastic cells and necrosis remains unclear. In this paper, 3 eyes with calcified retinoblastoma were examined by light microscope and electron microscope, and the electrical detection microscopic analysis was carried out. Materials and Methods Three eyes were excised and immediately dissected into McGoroeut Trump’s fixative. Von Kosssa’s calcium test