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食管、胃底静脉曲张破裂出血是临床危重病症,如肝功能好,经内科治疗止血后择期手术,病死率为9.5％;如内科治疗后仍出血,可急症手术,病死率达43.5％;如肝功能差而不能耐受手术,则取内科保守治疗。本病治疗旨在减少门静脉血流量和降低肝内血管阻力。 1.缩血管药物:①垂体后叶素:能使内脏小动脉收缩,门脉、奇静脉和胃左静脉的血流量下降,从而使门静压降低23％～36％。一般用0.2～0.6U/min持续静滴12～24小时,如出血停止,可减量继用12～24小时;如减量或停药后又出血,则重新给
Esophageal and gastric variceal bleeding is a clinical critically ill disease, such as liver function is good, after surgical treatment of hemostasis after elective surgery, the case fatality rate was 9.5%; such as bleeding after medical treatment, emergency surgery, mortality rate of 43.5%; such as Liver function is poor and can not tolerate surgery, then take conservative treatment. The treatment of this disease aims to reduce portal vein blood flow and reduce intrahepatic vascular resistance. 1. vasoconstrictor drugs: ① vasopressin: can visceral arterioles contraction, portal vein, azygos vein and left gastric vein blood flow decreased, so that the portal pressure decreased 23% to 36%. Generally 0.2 ~ 0.6U / min intravenous infusion of 12 to 24 hours, such as bleeding stopped, the reduction can be followed by 12 to 24 hours; such as reduction or withdrawal after bleeding, then re-give