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急性左心衰竭是缺血性心脏病、高血压性心脏病、主动脉瓣病或二尖瓣返流患者的常见死亡原因。许多研究业已证明扩张血管药物如酚妥拉明、硝普钠和硝酸甘油在心力衰竭治疗中的效用,但这些药物没有镇静作用,不能帮助病人消除不安、过度换气和呼吸困难的感觉。氯丙嗪作为一种主要的镇静剂,除镇静作用外,还有明显的扩张血管作用。本文报道氯丙嗪肌肉注射对急性左心衰竭的效用。
Acute left heart failure is a common cause of death in patients with ischemic heart disease, hypertensive heart disease, aortic valve disease, or mitral regurgitation. Many studies have demonstrated the utility of dilated vascular drugs such as phentolamine, sodium nitroprusside and nitroglycerin in the treatment of heart failure. However, these drugs have no sedative effect and do not help patients to relieve anxiety, hyperventilation and dyspnoea. Chlorpromazine as a major sedative, in addition to sedation, but also significantly dilate the blood vessels. This article reports the efficacy of intramuscular injection of chlorpromazine for acute left ventricular failure.