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目的:探讨低出生体重儿(LBW)宫外生长发育迟缓(EUGR)的相关因素,为LBW制定更合理的营养支持策略提供指导。方法:对2004年1月~2009年3月杭州市余杭区妇幼保健院住院的52例LBW进行体重的监测,并将其与中国15城市不同胎龄新生儿体重百分位数标准进行比较,统计LBW住院期间并发症的发生情况,应用多因素回归分析法,提出与EUGR有关的高危因素。结果:①52例LBW,出生时宫内发育迟缓(IUGR)的占36.54%,出院时存在EUGR的占73.08%,EUGR的发生率明显高于IUGR,差异有统计学意义(P﹤0.01)。②Logistic回归分析表明,EUGR有关的高危因素包括胎龄、出生体重、开奶日龄、疾病与并发症及是否合理应用肠外营养。结论:LBW发生EUGR的发生率很高,早期胃肠道喂养,防治各种并发症及积极合理的肠外营养,有助于减少EUGR的发生。
Objective: To explore the related factors of extrauterine growth retardation (EUGR) in low birth weight infants (LBW) and provide guidance for LBW to develop more reasonable nutritional support strategies. Methods: 52 cases of LBW hospitalized in Maternal and Child Health Hospital of Yuhang District of Hangzhou City from January 2004 to March 2009 were monitored for body weight, and compared with the weight percentiles of neonates of 15 gestational age in China. Statistical LBW incidence of complications during hospitalization, the use of multi-factor regression analysis, proposed EUGR-related risk factors. Results: (1) The LBW in 52 cases accounted for 36.54% of IUGR at birth, EUR accounted for 73.08% at discharge, and the incidence of EUGR was significantly higher than that of IUGR (P <0.01). Logistic regression analysis showed that the high risk factors associated with EUGR included gestational age, birth weight, age of open milk, diseases and complications, and whether rational use of parenteral nutrition. CONCLUSION: The incidence of EUGR is high in LBW. Early gastrointestinal feeding, prevention and treatment of various complications and positive and reasonable parenteral nutrition may help to reduce the occurrence of EUGR.