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志贺氏菌仍是目前在世界各地引起感染性腹泻流行的主要病原体,近年来分子生物学的理论和技术被逐步引入流行病学研究领域,并取到了很好的效果.本文就贺志贺氏菌的基因分型方法及其在流行病学研究中的应用作一综述.
Shigella is still the main causative agent causing infectious diarrhea all over the world. In recent years, the theories and techniques of molecular biology have been gradually introduced into the field of epidemiology and have achieved good results.In this paper, Genotyping method and its application in epidemiological studies are reviewed.