Methylation of Dickkopf-3 as a prognostic factor in cirrhosis-related hepatocellular carcinoma

• 作 者: Yang Bin Du Zhi Gao Ying-Ta
• 机 构: ThirdCentHosp,ThirdCentHosp,TianjinMedUniv,NankaiUniv,TEDA
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2010年6期
• 基金项目: Supported by China Postdoctoral Science Foundation,No. 20070410753,, Tianjin Science and Technology Commission, No.05YFSZSF02500,, Tianjin Health Bureau,No.07KZ10

AIM:To investigate the prevalence and time of Dickkopf(DKK) family methylation and its clinical significance in hepatocarcinogenesis. METHODS:Methylation of DKK family genes was quantitatively analyzed in 115 liver tissue samples,including 50 pairs of pri