Molecular Mechanisms Underlying the Time-dependent Autophagy and Apoptosis Induced by Nutrient Deple

• 作 者: 刘媛 陈燕 文璐 崔国惠
• 机 构: DepartmentofHematology
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2012年1期
• 关键词: multiple MYELOMA RPMI AUTOPHAGY APOPTOSIS Deptor Raf-/JNK/p/p NFκB multiple myel

This study explored the molecular mechanisms underlying the time-dependent autophagy and apoptosis induced by nutrient depletion in human multiple myeloma cell line RPMI8226 cells.RT-PCR and qRT-PCR were used to evaluate the transcriptional levels of Dept