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1987年1月至1991年1月我院住院治疗的重度妊高征患者共304例,其中经足量硫酸镁治疗后临床症状不缓解、平均动脉压≥18.7kPa 者21例,同时使用血管扩张剂治疗,取得较好效果.21例均为初产妇,30～36孕周18例,>37周3例,双胎3例.出现严重并发症21例次,其中眼底水肿、出血8例,肾功不全4例,心衰4例,低蛋白血症并贫血1例,IUGR2例,产后出血2例.根据使用药物种类不同分二组:一组10例,使用硝普钠50mg 加入5%葡萄糖液500ml 中静滴,以8～10滴/分开始,然后根据全身症状及降压效果来调整,一般维持在1～3μg/kg·min,须避光使用,配制后不
From January 1987 to January 1991, a total of 304 patients with severe PIH were hospitalized in our hospital. Among them, the clinical symptoms did not relieve after enough magnesium sulfate treatment. In 21 patients with mean arterial pressure ≥18.7kPa, vasodilation 21 cases were primipara, 30 to 36 gestational weeks in 18 cases,> 37 weeks in 3 cases, twins in 3. 21 cases of serious complications, including retinal edema, bleeding in 8 cases, 4 cases of renal insufficiency, 4 cases of heart failure, hypoproteinemia and anemia in 1 case, IUGR 2 cases, 2 cases of postpartum hemorrhage.According to the use of different types of drugs divided into two groups: a group of 10 cases, the use of sodium nitroprusside 50mg 5% Glucose solution 500ml in intravenous drip to 8 to 10 drops / min start, and then according to systemic symptoms and antihypertensive effect to adjust, generally maintained at 1 ~ 3μg / kg · min, to be protected from light, the preparation is not