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目的:观察坦索罗辛联合金匮肾气丸对前列腺增生(BPH)伴有勃起功能障碍(ED)的治疗效果。方法:102例BPH伴有ED(肾阳虚证)的患者,随机分为联合治疗组和坦索罗辛组。联合治疗组52例,给予口服坦索罗辛(0.2mg/d)联合金匮肾气丸(10g/d)治疗;对照组50例采用坦索罗辛(0.2mg/d)治疗,疗程3个月。治疗前后采用国际前列腺症状评分(IPSS)和国际勃起功能指数(IIEF-5)评分评价疗效。结果:治疗3个月后两组IPSS评分均显著降低、联合治疗组IIEF-5评分显著增加(P<0.05);坦索罗辛组IIEF-5评分无显著变化(P>0.05)。结论:坦索罗辛联合金匮肾气丸可显著改善BPH伴有ED症状。
Objective: To observe the effect of tamsulosin combined with Jingui Shenqi Pill on the treatment of benign prostatic hyperplasia (BPH) with erectile dysfunction (ED). Methods: A total of 102 patients with BPH accompanied with ED (Kidney-Yang Deficiency Syndrome) were randomly divided into combined treatment group and tamsulosin group. The combination therapy group (n = 52) received oral tamsulosin (0.2 mg / d) and Jing Kui Shen Qi Wan (10 g / d), and the control group received tamsulosin (0.2 mg / d) Months. Before and after treatment with the International Prostate Symptom Score (IPSS) and the International Index of Erectile Function (IIEF-5) score to evaluate the efficacy. Results: After 3 months of treatment, the IPSS scores of both groups were significantly decreased, while the IIEF-5 scores of the combined treatment group were significantly increased (P <0.05). There was no significant change in the tamsulosin IIEF-5 scores (P> 0.05). Conclusion: Tamsulosin combined with Jingui Shenqi Pills can significantly improve the symptoms of BPH associated with ED.