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青霉素G及其有关制剂青霉素G虽已使用了30年,但至今还用它治疗各种最常见的感染。甲组及乙组链球菌、肺炎双球菌、脑膜炎双球菌、淋病双球菌和梅毒螺旋体对之仍极敏感,尽管在这些年里发生了某种程度的抗药性。青霉素G结晶可静脉给药,或用长效的苄星青霉素行肌内注射;后者是预防和治疗甲组链球菌感染最有效的方法。在小儿患者,治疗梅毒或淋病时,普鲁卡因青霉素的使用似应适当限制,只在呕吐而不能口服青霉素G或青霉素V时,方宜短时间使用。
Penicillin G and its related agents Penicillin G, which has been in use for 30 years, has so far been used to treat the most common infections. Groups A and B streptococci, pneumococcus, meningococcus, gonorrhea and syphilis are still extremely sensitive to them, although some degree of resistance has occurred over these years. Penicillin G crystals can be administered intravenously, or intramuscularly with long-acting benzathine penicillin; the latter is the most effective way to prevent and treat Group A streptococcal infections. In pediatric patients, the treatment of syphilis or gonorrhea, the use of procaine penicillin should be appropriately limited, only vomiting and can not oral penicillin G or penicillin V, the parties should short-term use.