论文部分内容阅读
目的:探讨主动脉夹层致猝死的临床病理特点、发病机制及危险因素,提高其早期诊断及防治水平,降低病死率。方法:对2002-2007年7例主动脉夹层猝死病例进行临床尸检病理分析,总结其临床病理特点,分析发病机制及危险因素。结果:7例主动脉夹层猝死患者50岁以上4例,40岁以下3例,年龄30～71岁,平均(50.5±15)岁;多有主动脉粥样硬化和(或)高血压病史;临床表现最初大多为非心血管疾病症状。结论:主动脉夹层致病因素复杂,起病隐匿,常导致猝死;伴有长期高血压病、主动脉粥样硬化等高危人群出现突发性胸痛或休克表现时应警惕该病的发生并进行早期干预处理,降低患者病死率。
Objective: To investigate the clinicopathological features, pathogenesis and risk factors of sudden death caused by aortic dissection, to improve its early diagnosis and prevention and reduce the mortality. Methods: Seven cases of sudden death from aortic dissection between 2002 and 2007 were analyzed by pathology. The clinical and pathological features were summarized and the pathogenesis and risk factors were analyzed. Results: Of the 7 patients with sudden death from aortic dissection, 4 patients were over 50 years old and 3 patients under 40 years old, aged from 30 to 71 years (mean, 50.5 ± 15) years; most had a history of atherosclerosis and / or hypertension; Most of the initial clinical manifestations of non-cardiovascular disease symptoms. Conclusions: The causes of aortic dissection are complicated, the occult onset is occult, and often leads to sudden death. The occurrence of sudden chest pain or shock should be vigilant in the high risk population with long-term hypertension, aortic atherosclerosis and so on Early intervention to reduce patient mortality.