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观察依那普利治疗经临床及核素心血池扫描确诊的５０例左室舒张性心功能障碍患者的疗效。结果显示：治疗８周后，治疗组左房内径（ＬＡＤ）、室间隔厚度（ＩＶＳＴ）、左室重量指数（ＬＶＭＩ）显著降低；二尖瓣舒张早期充盈峰速（ＥＰＦＶ）、二尖瓣舒张晚期充盈峰速（ＡＰＦＶ）、二尖瓣舒张早、晚期充盈峰速比值（Ｅ／Ａ），二尖瓣舒张早期流速减速度（ＤＣ）及等容舒张时间（ＩＲＴ）均有改善；左室射血分数（ＬＶＥＦ）、心脏指数（ＣＩ）无明显变化；ＮＹＨＡ心功能级别改善、运动耐量显著提高。病人对依那普利耐受性良好。空白对照组上述各指标均无明显变化。提示依那普利是治疗左室舒张性心功能障碍患者的有效药物
To observe the efficacy of enalapril in the treatment of 50 patients with left ventricular diastolic heart dysfunction confirmed by clinical and radionuclide scan. The results showed that left atrial diameter (LAD), interventricular septum thickness (IVST) and left ventricular mass index (LVMI) were significantly decreased in treatment group after 8 weeks of treatment. Mitochondrial early peak filling velocity (EPFV) APFV, E / A, mitral early diastolic velocity (DC) and isovolumetric relaxation time (IRT) were all improved in the left ventricular The ejection fraction (LVEF), cardiac index (CI) had no significant change; NYHA heart function improved, exercise tolerance increased significantly. The patient is well tolerated with enalapril. The blank control group of the above indicators did not change significantly. Tip enalapril is effective in treating patients with left ventricular diastolic heart failure