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对60例系统性红斑狼疮患者作了临床分析,以女性发病为主,大部分病人有多脏器损害,最多见者为皮肤、关节、肾脏、心血管、神经精神症状以及浆膜炎等.三分之二以上病例有血液学异常,在诊断上以抗核因子及狼疮细胞的价值较大,阳性率亦较高.治疗上分为单独肾上腺皮质激素组和肾上腺皮质激素加免疫抑制剂联合组,并强调维持治疗的必要性,对病因和发病机理略作探讨.
The clinical analysis of 60 patients with systemic lupus erythematosus was made mainly in women. Most of the patients had multiple organ damage. The most common were skin, joint, kidney, cardiovascular, neuropsychiatric symptoms and serositis. More than two thirds of cases have hematological abnormalities, in the diagnosis of anti-nuclear factor and lupus cells larger value, the positive rate is also higher. Treatment is divided into separate adrenal cortical hormone group and adrenal cortex hormones plus immunosuppressive agents Group, and stressed the need to maintain treatment of etiology and pathogenesis of a little discussion.