论文部分内容阅读
目的探讨福辛普利的药效学和药代学特征,及临床应用情况,为其应用提供参考。方法通过参阅大量相关文献,作总结分析。结果与结论福辛普利主要通过阻断血管紧张素Ⅱ的形成而降低血压,该药物在原发性高血压和心力衰竭等患者中已显示其疗效。福辛普利具有肝脏、肾脏双重清除途径的特点。
Objective To investigate the pharmacodynamics and pharmacokinetic characteristics of fosinopril and its clinical application, and provide a reference for its application. Methods by referring to a large number of relevant literature, make a summary analysis. RESULTS AND CONCLUSION Fosinopril lowered blood pressure mainly by blocking the formation of angiotensin II, which has been shown to be effective in patients with essential hypertension and heart failure. Fosinopril has liver and kidney dual clearing pathways.