论文部分内容阅读
急性白血病的直接死亡原因大多是重症感染和出血。由于血小板输血的普及,因出血致死者有所减少,而因粒细胞减少伴发的重症感染相对增加。本文30例败血症在血培养后立即给氨基糖甙类(庆大霉素或托勃拉霉素)、广谱青毒素(磺苄青霉素或羧苄青霉素)、先锋霉素类药物。13例并用三种抗菌素,17例并用二种,7例并用粒细胞输血1～4次。诱导治疗前及不全诱导后发生的败血症,抗菌素疗效不佳,而缓解者抗菌素治疗均有效。7例粒细胞输血者不问骨髓状态如何,6例(85.7%)有效。无先行感染的败血症,抗菌素单独治疗的11例中6例有效,并用粒细胞输血的5例中4例有效;有先行感染在抗菌素使用过程中发生的败血症,抗菌素单独治疗的12例均无效,并用粒细胞输血的2例均有效。因此单
Most of the direct causes of acute leukemia are severe infections and bleeding. Due to the popularity of platelet transfusions, deaths due to bleeding have decreased, but due to neutropenia associated with severe infection is relatively increased. Septicemia in this paper 30 cases immediately after the blood culture to aminoglycosides (gentamicin or propofamycin), broad-spectrum penicillins (penicillin or carbenicillin), cephalosporins drugs. 13 cases and three antibiotics, 17 cases with two, seven cases with granulocytes transfusion 1 to 4 times. The induction of sepsis before and after induction of incomplete, antibiotic curative effect is poor, but the relief of antibiotics are effective. Six cases (85.7%) were effective regardless of bone marrow status in 7 patients with granulocyte transfusion. No prior infection of sepsis, antibiotic treatment of 11 cases, 6 cases of effective and 5 cases of granulocyte transfusion in 4 cases effective; first infection in the course of the use of antibiotics sepsis, antibiotic alone 12 cases were ineffective, Two cases of granulocyte transfusion were effective. So single