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目的探讨双环醇治疗慢性乙型肝炎的临床疗效及不良反应。方法选择152例在我院住院的慢性乙型肝炎患者,随机分成治疗组和对照组。其中对照组72例,给予肝泰乐、门冬氨酸钾镁、护肝片、维生素等综合护肝治疗;治疗组80例,在对照组治疗基础上加用双环醇25mg,3次/d,口服,共治疗3mo。结果疗程结束时,按疗效判定标准,治疗组临床显效率73.75%,总有效率92.5%;而对照组临床显效率63.89%,总有效率79.17%,有显著的统计学意义(P<0.05),未见严重的药物不良反应。结论双环醇是一种有效的慢性乙型肝炎治疗药物,且无毒副作用。
Objective To investigate the clinical efficacy and adverse reactions of bicyclol in the treatment of chronic hepatitis B. Methods 152 patients with chronic hepatitis B who were hospitalized in our hospital were randomly divided into treatment group and control group. In the control group, 72 cases were treated with Gutta-percha, Potassium magnesium aspartate, Hugan tablets, vitamins and so on. In the treatment group, 80 cases were treated with bicyclol 25mg three times a day , Oral, a total of 3mo. Results At the end of the course of treatment, the clinical effective rate was 73.75% and the total effective rate was 92.5% in the treatment group according to the criteria of curative effect, while the clinical effective rate was 63.89% and the total effective rate was 79.17% in the control group, with significant statistical significance (P <0.05) , No serious adverse drug reactions. Conclusion Bicyclol is an effective treatment for chronic hepatitis B with no toxic or side effects.