【摘 要】
：
Diffuse intestinal Kaposi’s sarcoma shares macroscopicand histopathologic features with gastrointestinal stromatumors. Correct diagnosis may pose a clinical ch
【机 构】
：
Department of Medicine 1 University Medical Center Hamburg-Eppendorf Hamburg Germany,Department of
【出 处】
：
World Journal of Gastroenterology
论文部分内容阅读
Diffuse intestinal Kaposi’s sarcoma shares macroscopicand histopathologic features with gastrointestinal stromatumors. Correct diagnosis may pose a clinical challengeWe describe the case of a young HIV-1-infected Africanlady without advanced immunodeficiency, who presentedwith a diffuse spindle cell tumor of the gut. Initiadiagnosis was of a gastrointestinal stromal tumor, basedon endoscopy and histopathology. Further evaluationrevealed evidence for human herpesvirus 8 (HHV8) andthe diagnosis had to be changed to diffuse intestinaKaposi’s sarcoma. Antiretroviral triple therapy togethewith chemotherapy was commenced, and has led to therapid remission of intestinal lesions. With a backgroundof HIV infection, the presence of HHV8 as the causativeagent of Kaposi’s sarcoma should be determined, asdistinct treatment is indicated.
Diffuse intestinal Kaposi’s sarcoma shares macroscopic and histopathologic features with gastrointestinal stromatumors. Correct diagnosis may pose a clinical challenge We describe the case of a young HIV-1-infected African lady without advanced immunodeficiency, who presented with a diffuse spindle cell tumor of the gut. Initiadiagnosis was of a gastrointestinal stromal tumor, based on endoscopy and histopathology. Further evaluationrevealed evidence for human herpesvirus 8 (HHV8) and the diagnosis had to be changed to diffuse intestina Kaposi’s sarcoma. Antiretroviral triple therapy to gethe with chemotherapy was commenced, and has led to therapid remission of intestinal lesions. With a backgroundof HIV infection, the presence of HHV8 as the causative agent of Kaposi’s sarcoma should be determined, asdistinct treatment is indicated.
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