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目的:评价新柏氏薄层液基细胞学检查、阴道镜下多点活检以及宫颈锥切术对宫颈上皮内瘤变的诊断及治疗。方法:回顾性分析380例宫颈液基细胞学筛查异常而进行阴道镜下多点活检以及宫颈锥切术的结果。结果:380例患者经液基细胞学筛查后,发现非典型鳞状上皮细胞80例,低度上皮内瘤变104例,高度上皮内瘤变196例;行阴道镜下多点活检后,CINⅠ级以下152例,CINⅡ以上228例;经宫颈锥切后,CINⅡ以下93例,CINⅡ以上135例。阴道镜下多点活检后CINⅡ阳性检出率显著高于液基细胞检查结果。结论:液基细胞学筛查、阴道镜下多点活检及宫颈锥切术对及早发现宫颈上皮内瘤变、避免宫颈癌的发生有重要意义。
OBJECTIVE: To evaluate the diagnosis and treatment of cervical intraepithelial neoplasia by thin layer liquid-based cytology, colposcopy biopsy and cervical conization. Methods: A retrospective analysis of 380 cases of cervical liquid-based cytology abnormalities under colposcopy biopsy and cervical conization results. Results: After liquid cytology screening, 380 patients were found in 80 cases of atypical squamous epithelial cells, 104 cases of low grade intraepithelial neoplasia and 196 cases of highly intraepithelial neoplasia. After colposcopy biopsy, There were 152 cases below CIN Ⅰ level and 228 cases above CIN Ⅱ level. After conization of the cervix, 93 cases were below CINⅡ and 135 cases above CINⅡ. Colposcopy multipoint biopsy CIN Ⅱ positive detection rate was significantly higher than liquid-based cell test results. Conclusion: Liquid-based cytological screening, multiple colposcopy biopsy and conization of the cervix have important significance for early detection of cervical intraepithelial neoplasia and avoidance of cervical cancer.