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目的:分析儿童Kimura病的临床特点,探讨儿童Kimura病的诊治方法及预后。方法:对我院2014年收治的1例儿童Kimura病进行报道,同时检索2005-2015年的中国医院知识总库(CHKD),收集资料完整的7例儿童Kimura病报道,对这8例Kimura病患儿的临床表现、实验室检查、治疗及预后进行综合分析。结果:儿童Kimura病主要表现为头颈部肿块、淋巴结肿大、大涎腺侵犯,外周血嗜酸粒细胞增多、血清Ig E水平升高,病灶边界不清无包膜,激素治疗有效,但容易复发。结论:Kimura病是一种罕见的、慢性的、病因不明的慢性炎性疾病,儿童Kimura病更加罕见,常表现为头颈部肿块,伴淋巴结肿大及大涎腺侵犯,手术、激素治疗有效,但容易复发。
Objective: To analyze the clinical features of children’s Kimura disease and explore the diagnosis and treatment of children’s Kimura disease and its prognosis. Methods: One case of Kimura disease was reported in our hospital in 2014. At the same time, CHKD was retrieved from 2005 to 2015 in China. A total of 7 cases of children with Kimura disease were collected. Eight cases of Kimura disease Children’s clinical manifestations, laboratory tests, treatment and prognosis of a comprehensive analysis. Results: Children with Kimura disease mainly showed head and neck mass, lymph node enlargement, salivary gland invasion, peripheral blood eosinophilia, elevated serum IgE levels, unclear border of the lesion, and effective hormone therapy. However, Easy to relapse. Conclusions: Kimura disease is a rare, chronic, chronic inflammatory disease of unknown etiology. Kimura disease in children is more rare and often presents as head and neck mass with lymph node enlargement and salivary gland invasion. Surgery and hormone therapy are effective , But easy to relapse.