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目的:对孕前及孕期妇女进行优生教育及产前筛查,分析这些孕妇的出生缺陷率,并和以往同地区的出生缺陷率进行对比。方法:对西北地区3826例孕妇孕前进行优生教育及相关的检查,孕中期进行产前筛查,主要是对孕中期孕妇血清甲胎蛋白(AFP)、绒毛膜促性腺激素B亚单位(Freeβ-HCG)检测,计算21-三体,18-三体,神经管缺陷进行风险评估,高风险的进一步作产前检查,最终降低出生缺陷率。结果:3826例孕妇总的出生缺陷率7.34‰,低于山西省全省的平均出生缺陷率。结论:将优生教育与产前筛查联合应用,可以降低出生缺陷率。
Objectives: Prenatal and prenatal care for prenatal education and prenatal screening, analysis of birth defects in these pregnant women, and birth defects in the same area with the previous comparison. Methods: 3826 pregnant women in Northwest China were educated with prenatal education and prenatal education. Prenatal screening was performed in the second trimester, which mainly focused on the serum levels of AFP and Freeβ- HCG) test, 21-trisomy, 18-trisomy, and neural tube defects were evaluated for risk assessment and high-risk prenatal tests were performed to ultimately reduce the birth defect rate. Results: The total birth defect rate of 3826 pregnant women was 7.34 ‰, which was lower than the average birth defect rate in Shanxi province. Conclusion: The combination of eugenics education and prenatal screening can reduce the birth defect rate.