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糖尿病已成为严重威胁国人健康的最重要的慢性非传染性疾病之一[1]。引起的大血管和微血管并发症是糖尿病患者死亡的主要原因[2]。目前胰岛素治疗应用日趋广泛,早起应用胰岛素对保护胰腺β细胞及减少并发症具有重要意义。二甲双胍与胰岛素联用可减少体重增加,减少外源性胰岛素用量[3]。α-葡萄糖苷酶抑制剂与胰岛素联用在有效改善血糖的同时,减少胰岛素使用剂量,减少体重增加的幅度和趋势[4-6]。因此,在无禁忌症的2型糖尿病患者中均
Diabetes has become one of the most important chronic non-communicable diseases that threaten the health of Chinese people [1]. Caused by major vascular and microvascular complications is the leading cause of death in patients with diabetes [2]. Currently insulin treatment is widely used, early application of insulin on the protection of pancreatic β cells and reduce complications of great significance. Metformin and insulin can reduce weight gain and reduce the amount of exogenous insulin [3]. In combination with insulin, α-glucosidase inhibitor and insulin can effectively reduce blood glucose, reduce insulin dosage and reduce the magnitude and trend of weight gain [4-6]. Therefore, in patients with type 2 diabetes without contraindications