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患儿男,10个月,全身多发结节1个月。皮肤科情况:头皮、额头、臀部、双下肢、双足、阴囊散在分布红褐色结节,黄豆至豌豆大小,表面无破溃。皮损组织病理示:真皮浅层可见灶状或片状分布的组织细胞样细胞,胞质丰富,淡嗜伊红染,核椭圆形,有核沟,核分裂偶见。并见散在淋巴细胞、中性粒细胞浸润。免疫组织化学:CD1a(+),S-100(+)。皮疹在3个月内自行消退。诊断:先天性自愈性朗格汉斯组织细胞增生症。
Children male, 10 months, systemic multiple nodules 1 month. Dermatology: scalp, forehead, buttocks, lower extremities, both feet, scrotal scattered distribution of reddish brown nodules, soybeans to pea size, the surface without ulceration. Histopathological lesions showed: the superficial dermis can be seen focal or flaky distribution of tissue-like cells, rich cytoplasm, light eosinophilic staining, nuclear oval, nuclear ditch, occasionally nuclear fission. See scattered in lymphocytes, neutrophil infiltration. Immunohistochemistry: CD1a (+), S-100 (+). The rash subsided within 3 months. Diagnosis: Congenital self-healing Langerhans cell histiocytosis.