Effects of primary microglia and astrocytes on neural stem cells in in vitro and in vivo models of i

• 作 者: Sheng-Jun Wen Xi-Min Zheng Li-
• 机 构: DepartmentofNeurology
• 出 处: 中国神经再生研究:英文版
• 发表日期: 2021年9期
• 关键词: ASTROCYTES GLUTAMATE MICROGLIA neural stem cells NEUROGENESIS neurons PEROXIDE r
• 基金项目: supported by the National Natural Science Foundation of China,Nos.81371213,81070987,30971531,grants from the Ministry of Science and Technology of China,Nos.2010CB945600,2010CB945601(all to QLY)

Transplantation of neural stem cells(NSCs) can protect neurons in animal stroke models;however, their low rates of survival and neuronal differentiation limit their clinical application. Glial niches, an important location of neural stem cells, regulate s