Protective effect of sodium ferulate on cardiac hypertrophy in spontaneously hypertensive rats

• 作 者: CHEN Pan-pan LI Zhong-li JIN F
• 机 构: KeyLaboratoryofBasicPharmacologyofMinistryofEducationandJointInternationalResearchLaboratoryofEthnom
• 出 处: 中国药理学与毒理学杂志
• 发表日期: 2019年9期
• 关键词: sodium FERULATE spontaneously HYPERTENSIVE rats CARDIAC HYPERTROPHY calcium-sens
• 基金项目: National Natural Science Foundation of China(81860732),Scientific and Technological Projects for Social Develop ment in Guizhou Province of China([2011]3036),the State Key Laboratory of Cardiovascular

OBJECTIVE To investigate the inhibitory effect and mechanism of sodium ferulate(SF)on myocardial hypertrophy in spontaneously hypertensive(SHR).METHODS Forty 14-week-old SHR male rats were randomly divided into model group(SHR,receive distilled water)and