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为探讨脑缺血对下丘脑一垂体一肾上腺皮质轴(HPA)功能的影响,采用改良的O’Brien法,夹闭兔左侧大脑中动脉(MCA),形成局灶性脑缺血(MCAO)动物模型,应用放免测定法对MCAO家兔血清促肾上腺皮质激素(ACTH)、皮质醇(Cor)含量进行检测。材料18只体重1.5~2.0kg雌性混
To investigate the effect of cerebral ischemia on hypothalamic-pituitary-adrenal cortex axis (HPA) function, a modified O’Brien method was used to occlude the left middle cerebral artery (MCA) in rabbits to establish focal cerebral ischemia (MCAO ) Animal models, the application of radioimmunoassay of MCAO rabbit serum adrenocorticotropic hormone (ACTH), cortisol (Cor) content were detected. Material 18 body weight 1.5 ~ 2.0kg female mixed