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作者对25例经肝活检证实的慢性乙型肝炎患者,在 HBeAg、HBV-DNA 和 DNA 多聚酶从血清中消失后,随访25±2个月。患者包括男性23例(92%),女性2例(8%)。22例(88%)白人,2例东方人,1例黑人,年龄22～67岁,平均40±12岁。14例(56%)以往曾接受皮质激素治疗(2例并用硫唑嘌呤),6例接受过单磷酸阿糖腺苷抗病毒治疗。这些药物均是患者血清 HBeAg阳性时给予的,用药期间 HBeAg 皆未转阴。血清 HBsAg、抗-HBs 和抗-HBc 用 RIA 法
The authors of 25 patients with chronic hepatitis B confirmed by liver biopsy in patients with HBeAg, HBV-DNA and DNA polymerase disappeared from the serum, followed up for 25 ± 2 months. Patients included 23 males (92%) and 2 females (8%). 22 (88%) white, 2 Oriental, 1 black, aged 22 to 67 years, an average of 40 ± 12 years old. Fourteen patients (56%) had received corticosteroids (2 in the past with azathioprine) and 6 had been treated with the adenosine monophosphate adenovirus. These drugs are given in patients with HBeAg-positive serum, HBeAg were not negative during treatment. Serum HBsAg, anti-HBs and anti-HBc by RIA method