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目的:探讨血清中TTR、IGFBP-3含量在早产儿出生后早期生长发育过程中的变化,为精确评价早产儿营养状态提供理论依据。方法:将73例早产儿中28周≤胎龄<30周15例为Ⅰ组,30周≤胎龄<32周29例为Ⅱ组,32周≤胎龄<34周29例为Ⅲ组,分别测定3组中早产儿生后第1、7、14天血清TTR、IGFBP-3含量并进行比较。结果:3组早产儿出生第1天TTR含量各组两两比较差异有统计学意义(P<0.05);在出生第1、7、14天时血清TTR含量随日龄增长明显增高,IGFBP-3含量生后7天增高显著,差异有统计学意义(P<0.05)。结论:血清TTR、IGFBP-3含量对评估早产儿生后早期营养状况有一定的价值。
OBJECTIVE: To investigate the changes of TTR and IGFBP-3 levels in preterm infants after birth and to provide a theoretical basis for accurate assessment of nutritional status of premature infants. Methods: Totally 73 preterm infants with gestational age ≤30weeks were treated as group Ⅰ, 30weeks ≤ gestational age <32weeks and 29were treated as group Ⅱ, 32weeks ≤weeks <34weeks and 29were treated as stage Ⅲ, The levels of TTR and IGFBP-3 in sera of preterm infants after 3, 7, 14 days were measured and compared. Results: There was significant difference in the TTR content between the first day of birth and the first day of birth (P <0.05). The serum TTR levels increased significantly with the increase of age on the 1st, Content increased significantly 7 days after birth, the difference was statistically significant (P <0.05). Conclusion: The levels of serum TTR and IGFBP-3 have some value in assessing the nutritional status of premature infants after birth.