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职业接触多环芳烃类化合物 (ＰＡＨｓ)是与癌症发生有关的一个危险因素 ,其在人体内的代谢存在个体差异。本研究探讨细胞色素Ｐ450 1Ａ1 (ＣＹＰ1Ａ1 )和 2Ｅ1 (ＣＹＰ2Ｅ1 ) ,谷胱甘肽Ｓ 转移酶 μ(ＧＳＴＭ1 )和θ(ＧＳＴＴ1 )的基因多态性对ＰＡＨｓ代谢产物 1 羟基芘 (1
Occupational exposure to polycyclic aromatic hydrocarbons (PAHs) is a risk factor associated with the development of cancer, and its individual metabolism in the human body there are individual differences. This study investigated the effects of genetic polymorphisms of cytochrome P450 1A1 (CYP1A1), 2E1 (CYP2E1), glutathione S transferase μ (GSTM1) and θ (GSTT1) on the metabolism of PAHs 1 hydroxy pyrene