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目的分析2006—2008年南京地区抗感染药物应用状况及趋势,为临床合理应用抗感染药及其科学管理提供依据。方法应用金额排序法和用药频度排序法,对南京地区22家医院2006—2008年临床使用的抗感染药物进行统计和分析。结果 2006—2008年抗感染药物用药总额增长迅速,年平均增长率达33.23%。其中β内酰胺类药物及喹诺酮类药物占市场份额的70%左右,位于DDDs排序前列的为左氧氟沙星和罗红霉素。结论 2006—2008年南京地区抗感染药物各品种使用情况比较稳定,但仍应加强对于β内酰胺类、喹诺酮类及大环内酯类等药物的管理,以提高药物疗效,减少药物耐药性。
Objective To analyze the status and trends of anti-infectives application in Nanjing from 2006 to 2008, and provide evidences for rational use of anti-infectives and their scientific management. Methods The amount ranking method and medication frequency ranking method were used to count and analyze anti-infective drugs used clinically in 2006-2008 in 22 hospitals in Nanjing. Results The total amount of anti-infective drugs increased rapidly from 2006 to 2008, with an average annual growth rate of 33.23%. Among them, β-lactam drugs and quinolones account for about 70% of the market share, and levofloxacin and roxithromycin ranked the top of DDDs. Conclusion The use of anti-infectives in Nanjing was stable in 2006-2008, but the management of β-lactams, quinolones and macrolides should be strengthened so as to improve the curative effect and reduce the drug resistance .