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目的探讨加巴喷丁联合奥施康定治疗癌性神经病理性疼痛的疗效。方法将67例患者按随机化原则分为A组36例和B组31例,A组予奥施康定、加巴喷丁联合镇痛治疗,B组奥施康定单药镇痛治疗;治疗2周后分析疗效。结果 A组有效率为94.4%明显高于B组的77.4%,差异有统计学意义(P<0.05);A组患者Karnofsky评分提高+稳定者35/36(97.2%)明显高于B组的25/31(80.6%),差异有统计学意义(P<0.05);2组不良反应无明显差异。结论加巴喷丁联合奥施康定治疗癌性神经病理性疼痛疗效好,不良反应小,简便易行,值得推广。
Objective To investigate the curative effect of gabapentin combined with oxycodone on malignant neuropathic pain. Methods According to the principle of randomization, 67 patients were divided into group A (36 cases) and group B (31 cases), group A was treated with oxsiconkine and gabapentin, and group B was given ovastatin alone. After 2 weeks of treatment, Efficacy. Results The effective rate of group A was 94.4%, which was significantly higher than that of group B (77.4%), the difference was statistically significant (P <0.05). In group A, the Karnofsky score was increased and the stability was 35/36 (97.2%) 25/31 (80.6%), the difference was statistically significant (P <0.05); two groups of adverse reactions no significant difference. Conclusion Gabapentin combined with Oxocodin has good curative effect on malignant neuropathic pain and has a small adverse reaction, which is simple and easy to be implemented and worthy of promotion.