急性低氧条件下脑血流的自动调节

• 作 者: 顾正中 石中瑗 王利华 王金根
• 机 构: 交通部石油部海洋水下工程科学研究院,交通部石油部海洋水下工程科学研究院,中国科学院上海生理研究所,中国科学院上海生理研究所 上海,上海
• 出 处: 科学通报
• 发表日期: 1983年17期
• 关键词: 脑血流自动调节 急性低氧 脑血流 内在能力 颅内高压 脑灌注压 生理调节 脑血管 颅内压 常氧

自Fog用颅窗技术证明了脑血管具有自动调节能力以来,已有许多研究者证实了这一重要的生理调节现象。脑血流自动调节是指脑灌注压(平均动脉压—颅内压)在一定范围内变化时,脑仍能维持其稳定血流的一种内在能力。有关低氧对脑血流自动调节能力的影响,国外已有报道。这些研究均在麻醉或麻痹条件下进行。至于在低氧清醒以及低氧颅内高压条件下的脑血流自动调节能力研究,报道甚少。

Since Fog craniofacial technology proved that cerebral blood vessels have the ability to automatically regulate, many researchers have confirmed this important physiological regulation phenomenon. Auto-regulation of cerebral blood flow refers to an intrinsic ability of the brain to maintain its steady blood flow when cerebral perfusion pressure (mean arterial pressure - intracranial pressure) changes within a certain range. The impact of hypoxia on the ability of cerebral blood flow auto-regulation, has been reported abroad. These studies were conducted under anesthesia or paralysis. As for hypoxic awake and hypoxic conditions of cerebral blood flow under the conditions of the ability to automatically regulate the research, few reports.