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摘自《医学参考报营养学频道》2014年8月第8期期【据《J Pediatr Gastroenterol Nutr》2013年9月报道】题:天冬氨酸氨基转移酶与血小板比值与肠衰竭儿科患者的肝硬化相关而与其肝纤维化无关(作者Díaz JJ等)肠衰竭(intestinal failure,IF)的儿科患者只能通过肠外营养(parenteral nutrition,PN)支持来获得足够的营养用于生长发育,而长期的PN将造成明显的肝脏损害。本次研究的目的是分析非损伤性实验室检测指标:天冬氨酸氨基转移酶与血小板比值(aspartate aminotransferase to platelet ratio index,APRI)对于肠衰竭患儿相关性肝病的诊断。西班牙Asturias中央大学医院的Díaz等回顾性收集了2006年1月到2010年11月所有在波士顿儿童医院接受PN和
From the Medical Reference Daily Nutrition Channel, Issue 8, August 2014 [Reported by J Pediatr Gastroenterol Nutr, September 2013] Title: Aspartate aminotransferase to platelet ratio in patients with intestinal failure and liver failure in pediatric patients Sclerosis has nothing to do with its liver fibrosis (by Díaz JJ et al.) Pediatric patients with intestinal failure (IF) are only able to gain adequate nutrition for growth through parenteral nutrition (PN) support, whereas long-term The PN will cause significant liver damage. The purpose of this study was to analyze the non-invasive laboratory test aspartate aminotransferase to platelet ratio index (APRI) for the diagnosis of liver disease in children with intestinal failure. Díaz et al at Asturias Central University Hospital in Spain retrospectively collected all data from January 2006 to November 2010 at Boston Children’s Hospital receiving PN and