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抗精子抗体是由于精子或精浆中的抗原类物质刺激机体通过同种免疫或自身免疫而产生,包括Ig A、Ig G、Ig M、Ig E等类型,抗精子抗体可抑制精子活动、干扰精子的获能等多个环节,导致不孕不育的发生[1]。近年来,免疫性因素导致的不孕不育已经成为困扰适龄生育人群的重要问题[2]。有资料估计,临床上大约20%的不孕不育是由于免疫性因素导致的,其中抗精子抗体阳性导致的免疫性不孕被认为是导致不孕不育的重要原因之一[3]。调查报
Anti-sperm antibodies are produced by sperm or seminal plasma antigenic substances to stimulate the body through alloimmunity or autoimmunity, including IgA, IgG, IgM, IgE and other types of anti-sperm antibodies can inhibit sperm motility, interference Sperm and other aspects of the ability to be acquired, leading to the occurrence of infertility [1]. In recent years, the infertility caused by immune factors has become an important issue plaguing the reproductive age group [2]. It is estimated that about 20% of clinically infertility is due to immune factors, of which immunostimulatory infertility caused by anti-sperm antibodies is considered to be one of the important causes of infertility [3]. Investigation report