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目的:比较国产生长抑素与进口生长抑素治疗消化性溃疡出血的经济效果。方法:将120例消化性溃疡伴出血的患者随机分成国产生长抑素及进口生长抑素组,分别给予国产生长抑素、进口生长抑素治疗3天,观察疗效,并进行药物经济学评价。结果:国产生长抑素、进口生长抑素治疗上消化道出血成本分别为558元和4116元,有统计学差异(P<0.05);有效率分别为92.5%和96.8%,无统计学差异(P>0.05),成本—效果比分别为603.24和4252.07,有统计学差异(P<0.05)。结论:从药物经济学角度分析,国产生长抑素治疗消化性溃疡出血较进口生长抑素更为经济。
Objective: To compare the economic effects of domestic somatostatin and somatostatin in the treatment of peptic ulcer bleeding. Methods: A total of 120 patients with peptic ulcer and hemorrhage were randomly divided into domestic somatostatin and somatostatin. The patients were given domestic somatostatin and imported somatostatin for 3 days respectively. The curative effect was observed and evaluated by pharmacoeconomics. Results: The costs of domestic somatostatin and imported somatostatin in treatment of upper gastrointestinal bleeding were 558 yuan and 4116 yuan, respectively, with statistical significance (P <0.05); the effective rates were 92.5% and 96.8% respectively, with no significant difference P> 0.05), the cost-effectiveness ratio was 603.24 and 4252.07 respectively, with statistical significance (P <0.05). Conclusion: From the perspective of pharmacoeconomics, domestic somatostatin treatment of peptic ulcer bleeding more economical than the import of somatostatin.