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24例老年高血压病 期患者 ,服用硝苯啶 4年以上。服药前经超声心动图检查 ,证实有左室肥厚。服药 2年后 ,收缩压、舒张压、左室重量 (L VM)与左室重量指数 (L VMI)都有显著的降低 ,左室收缩与舒张功能有所改善。服药 4年后 ,收缩压与舒张压继续有所下降 ,但 L VM与 L VMI有所回升 ,与治疗前相比 ,则无显著差异。表明经硝苯啶 4年治疗 ,左室肥厚程度保持原有水平 ,左室收缩与舒张功能获得改善
24 elderly hypertensive patients, taking nifedipine more than 4 years. Before taking the echocardiography, confirmed that left ventricular hypertrophy. Two years after taking the medication, systolic blood pressure, diastolic blood pressure, left ventricular mass (L VM) and left ventricular mass index (L VMI) were significantly reduced, left ventricular systolic and diastolic function improved. After 4 years of medication, systolic and diastolic blood pressure continued to decline, but L VM and L VMI increased slightly, compared with those before treatment, there was no significant difference. That nifedipine 4-year treatment, left ventricular hypertrophy to maintain the original level, left ventricular systolic and diastolic function improved