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目的分析急性脑膜炎/脑炎综合征(AMES)病例的流行特征和临床诊断分类。方法在济南市选取省、市、县级各2所医院作为哨点医院,对2008-2009年报告的AMES病例进行个案调查并收集临床诊断等资料。结果 2008-2009年共报告AMES病例699例,其中2008年369例,2009年330例;2年报告的AMES病例均在7~9月呈现高峰,济南市籍与非济南市籍病例数基本持平,男女性别比为1.75∶1,10岁以下儿童占70%以上(发病年龄中位数为7岁),且以学生、散居儿童、托幼儿童为主。AMES病例的入院诊断中,属于病毒性感染者为574例,占82.12%,细菌感染者为73例,占10.44%。结论 AMES是临床常见且具有流行特征的综合征,目前入院诊断以病毒性感染为主。今后应加强AMES病例的监测和防控工作。
Objective To analyze the epidemiological features and clinical diagnosis of acute meningitis / encephalitis syndrome (AMES). Methods Two hospitals at provincial, city and county level were selected as sentinel hospitals in Jinan City. The case reports of AMES cases reported in 2008-2009 and clinical diagnosis data were collected. Results A total of 699 cases of AMES were reported in 2008-2009, including 369 cases in 2008 and 330 cases in 2009. The AMES cases reported in 2-year peaked from July to September, and the number of Jinan municipal and non-Jinan municipalities was basically the same . The male-to-female ratio was 1.75: 1. Children under 10 years old accounted for over 70% (median age of onset was 7 years old), and were mainly students, diasporas and kindergarten children. Among the cases of AMES admitted to hospital, 574 cases were viral infections, accounting for 82.12%, and 73 cases were bacterial infections, accounting for 10.44%. Conclusions AMES is a common clinical syndrome with epidemic features. At present, the diagnosis of viral infections is the most common in hospital. In the future, the monitoring and prevention and control of AMES cases should be strengthened.