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为探讨胎儿完全房室传导阻滞宫内起搏治疗的可能性，本文采用6例羊胎作为研究对象，通过开腹剖宫的方式，对羊胎实行了经静脉右心室心内膜起搏，测定了三种情况下右心室输出量并对三尖瓣关闭不全的程度作了半定量测定，6例羊胎经静脉起搏电极的插入均顺利完成，右心室输出量测定结果如下：起搏电极前端留置在上腔静脉时（基准值）：107．0±13．3ml·kg－1·min；起搏电极前端经三尖瓣插入右心室后，右心输出量减少到73．8±175ml·kg－1·min（P＜0．05）；以200／分的频率右心室起搏后，右心输出量为78．3±23．6ml·kg－1·min；三尖瓣反流的半定量测定（三尖瓣反流信号／右房面积）：起搏电极前端在上腔静脉留置时（基准值），三尖辩反流信号右房之比为0．13±0．047；起搏电极前端经三尖瓣插入右室后为0．16±0．089；以200／分频率右心室起搏时，该比值为0．16±0．089。三种情况下，三尖瓣反流的程度无明显差别（P＞0．05）。本文结果表明，通过手术的方式给胎儿安植心脏起搏器是完全可行的。
In order to explore the possibility of intrauterine parenchyma treatment of fetal complete AV block, we use 6 cases of sheep as the research object, through the open cesarean section, the sheep fetus by intravenous right ventricular endocardial pacing , The right ventricular output was measured and the degree of tricuspid regurgitation was measured semi-quantitatively. The insertion of 6 cases of sheep by transvenous pacing electrode was successfully completed. The results of right ventricular output were as follows: When the anterior electrode of the pacing electrode was placed in the superior vena cava (reference value): 107.0 ± 13.3ml · kg-1 · min, the right cardiac output decreased to 73.8 ± 175ml · kg-1 · min (P <0.05). Right ventricular pacing at a frequency of 200 / min resulted in a right ventricular output of 78.3 ± 23.6ml · kg-1 · min. Semi-quantitative analysis of reflux (tricuspid regurgitant signal / right atrial area): When the apical pacing electrode was placed in the superior vena cava (reference value), the ratio of the right atrial counterreversion signal was 0.13 ± 0 .047; Pacemaker electrode tip was inserted into the right ventricle after tricuspid valve was 0.16 ± 0.089; to 200 / min frequency of right ventricular pacing, The ratio is 0.16 ± 0.089. In all three cases, there was no significant difference in the degree of tricuspid regurgitation (P> 0.05). The results of this paper show that it is totally feasible to implant pacemakers into the fetus through surgery.