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目的利用MRI对不同年龄段成人正常前列腺进行定量研究,探讨前列腺老年化改变的影像学特点及其演变规律。资料与方法选取579名正常志愿者,根据年龄段的不同分为5个组(20～29岁,30～39岁,40～49岁,50～59岁,60岁以上),测量前列腺整体和中央区各自的径线、体积数值,并计算中央区体积占前列腺总体积的比例;分别测量前列腺中央区和外周带的T1、T2值,比较分析不同年龄段上述各项测量值的变化特点。结果前列腺整体体积范围约在11.59～47.01cm3之间,其上下径、前后径、左右径、体积随年龄增加而增大,差异具有统计学意义(P<0.05)。前列腺中央区体积约在2.89～12.46cm3之间,其上下径、前后径、左右径、体积随年龄增加而增长,中央区体积占前列腺总体积百分比约为22%～36%,其随着年龄增大呈比例增加,差异具有统计学意义(P<0.05)。年龄不同的条件下,各年龄段外周带的T1、T2值随着年龄增加逐渐增大,差别均有统计学意义(P<0.05);各年龄段中央区T1、T2值随着年龄增加未见明显变化,差异无统计学意义(P>0.05)。结论前列腺整体和中央区的各个径线、体积随年龄增加而增长,中央区所占总体体积随着年龄的增大呈比例增加,但是基本保持在一定范围之内。前列腺外周带的T2信号强度随着年龄增长逐渐增强,T1信号强度随着年龄增长逐渐减弱;中央区的T1、T2信号强度则无明显变化。
Objective To quantitatively study the normal prostate in adults of different ages by using MRI to explore the imaging characteristics and the evolution of the senile changes of the senility. Materials and Methods 579 normal volunteers were selected and divided into five groups (20-29 years old, 30-39 years old, 40-49 years old, 50-59 years old, 60 years old or older) according to the different age groups. The total prostate and The central region of their respective diameter and volume values, and calculate the central volume of the total prostate volume ratio; measured in the central and peripheral prostate of the T1, T2 values, comparative analysis of the different characteristics of different ages above-mentioned measurements. Results The overall volume of the prostate was about 11.59 ~ 47.01cm3. The diameter of the upper and lower anterior, posterior diameter, left and right diameter, volume increased with age, the difference was statistically significant (P <0.05). Prostate central volume of about 2.89 ~ 12.46cm3 between its diameter, anteroposterior diameter, left and right diameter, volume increases with age, the central volume accounted for the total volume of the prostate about 22% to 36%, which with age Increasing the proportion increased, the difference was statistically significant (P <0.05). The T1 and T2 values of the peripheral zone in all age groups gradually increased with the increase of age under the different age conditions (P <0.05). The T1 and T2 values in the central zone of each age group did not increase with age See significant changes, the difference was not statistically significant (P> 0.05). Conclusion The diameter and volume of the whole prostate and the central region increase with the increase of age. The total volume of the central region increases proportionally with age, but remains within a certain range. T2 signal intensity in peripheral zone of prostate gradually increased with age, T1 signal intensity gradually weakened with age; there was no significant change in T1, T2 signal intensity in central area.