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粒细胞集落刺激因子是一种骨髓干细胞动员剂,能刺激骨髓干细胞分化为肝细胞,并定植于受损的肝脏。本研究运用重组人粒细胞集落刺激因子(hrG-CSF)治疗亚急性肝损伤小鼠模型,通过血清学、病理等指标变化来分析其对亚急性肝损伤的保护作用。材料与方法一、实验动物清洁级、体重(23
Granulocyte colony-stimulating factor is a mobilization agent of bone marrow stem cells that can stimulate bone marrow stem cells to differentiate into hepatocytes and colonize the damaged liver. This study used recombinant human granulocyte colony-stimulating factor (hrG-CSF) to treat subacute liver injury model in mice. The protective effects of hrG-CSF on sub-acute liver injury were analyzed by serological and pathological changes. Materials and methods First, the experimental animal cleaning grade, weight (23